Sure, Call of Duty has long replaced Guitar Hero as the apple of Bobby Kotick's eye, the now departed music franchise still has something to brag about. NPD just released a list of the top ten games of all time in terms of dollar (not unit) sales, and Black Ops has sold the most units, Guitar Hero III has still earned more money than any game ever.
The list is compiled by total dollar sales, so it's largely dominated by games that came with expensive pack-in peripherals, like Guitar Hero, Rock Band, and Nintendo's Wii Fit.
1. Guitar Hero III: Legends of Rock -- Activision -- $830.9 million
2. Call of Duty: Black Ops -- Activision -- $787.4 million
3. Wii Fit -- Nintendo -- $736.6 million
4. Call of Duty: Modern Warfare 2 -- Activision -- $713.6 million
5. Rock Band--MTV Games -- $670.7 million
6. Wii Play -- Nintendo
7. Guitar Hero World Tour -- Activision
8. Wii Fit Plus -- Nintendo
9. Mario Kart Wii -- Nintendo
10. Call of Duty 4: Modern Warfare -- Activision