GameInformer

If it was me, I'd get  "Uncharted 2".

Are you seriously even considering what you just said? Uncharted 2 is a surefire bet.

Well, actually I forgot to mention something. If I got Uncharted 2, I would also get Battlefield: Bad Company with it because I would get the special package from Wally World.

I also prefer First-Person view better than Third-Person. (But that had just recently changed.)

Metal Gear Solid 4 would be a great choice if you are fan of the series.

Little Big Planet if you wanna try something totally NEW...

Final Fantasy XIII and God of War III

Uncharted 2

Final Fantasy 13 all the way unless you fancy fps cause then I would suggest BFBC2

what kind of game do u want??? if u like or have read the book Divine Comedy and liked it then i highly recommend Dante's Inferno.  This game pits you as Dante against every force in hell including Lucifer himself in an attempt to get back your beloved Beatrice. It's great throughout the game you get to either absolve or damned various famous people like electra, pontius pilate, etc.

Honestly go with oblivion. Its an amazing singleplayer experience that will not let you leave the couch for at least a week.

Demon's Souls was amazing, try that

bioshock 2 i'm playin and its sick

What do you guys think of Disgaea 3: Absence of Justice? Its really cheap right now and I could use a JRPG or two. Is the gameplay any good in your opinion?

To add to the games that have been said:

Resistance1 and 2 (this game is a fps with ratchet and clanks style guns)

and from psn store:  

final fantasy 7 is a classic (dated to people who are not fanatics)

most of the Pixel Junk series will hit some soft spots depends on your genre.

Some of my personal faves..

Beyond Good & Evil

Shin Megami Tensei Nocturne

Digital Devil Saga I & II

Legend of Dragoon

Legaia I & II

Rogue Galaxy

Fatal Frame Series

When it comes out lost planet 2 looks like a great game