InSane – little was known about InSane. Guillermo del Toro, the film director behind Pan's Labyrinth and Hellboy was working on it and it was supposed to be "...a very different type of horror game. It's not survival horror. It's truly a strange, geeky mix. It's a Lovecraftian thing," according to del Toro. Whatever it was going to be, it's done now.

Brothers in Arms: Furious 4 (Xbox 360, PlayStation 3) – Furious 4 wasn't so much cancelled as much as it has been retooled into something different. We don't know what it will be just yet, but it won't be called Brothers in Arms.

Sadness (Wii) – Sadness was announced early in the Wii's life-cycle, and it had a a lot of promise. The game was about a woman protecting her blind, paranoid schizophrenic, narcoleptic son in pre-World War I Ukraine. The game was going to be entirely in black and white, but during its four years of troubled development, the game was never shown playable.

Theseis (Xbox 360, PlayStation 3) – Theseis was going to be God of War/Tomb Raider-esque action game following the exploits of two Greek treasure hunting journalists who dabble in paranormal research. Alas, the game was too ambitious for its own good, and never made it through development.

Gun Loco (Xbox 360, PlayStation 3) – Gun Loco was a Square Enix third-person shooter parkour title that placed characters in the shoes of an ex-convict fighting for survival on a prison planet. The game was canceled recently. You can read a larger preview of the game here, and read about its cancellation here.

Frame City Killer (Xbox 360, PlayStation 3) – Frame City Killer put you in the shoes of an undercover agent in a future Asian city, pulling off assorted assassinations and performing Heavy Rain-like detective sequences on your journey to eliminate a deadly drug called Visual Acid.